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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BLM
All Species:
16.36
Human Site:
S1286
Identified Species:
27.69
UniProt:
P54132
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54132
NP_000048.1
1417
159000
S1286
I
S
V
L
Q
K
Y
S
E
W
T
S
P
A
E
Chimpanzee
Pan troglodytes
XP_510594
1417
158822
S1286
I
S
V
L
Q
K
Y
S
E
W
T
S
P
A
E
Rhesus Macaque
Macaca mulatta
XP_001097543
1416
158885
S1285
I
S
V
L
Q
K
Y
S
E
W
T
S
P
A
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O88700
1416
158347
P1285
K
Y
G
A
E
V
I
P
V
L
Q
K
Y
S
E
Rat
Rattus norvegicus
Q6AYJ1
621
69624
A495
N
I
T
E
H
C
Q
A
L
I
K
I
L
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515695
791
89186
K665
L
P
A
G
G
D
D
K
D
P
S
W
L
S
P
Chicken
Gallus gallus
Q9I920
1142
126164
S1016
I
K
V
M
D
K
Y
S
E
W
T
T
P
E
D
Frog
Xenopus laevis
Q9DEY9
1364
152305
S1238
I
D
V
L
Q
K
Y
S
E
W
T
L
P
V
E
Zebra Danio
Brachydanio rerio
XP_701357
1261
139417
R1135
F
L
G
S
K
S
A
R
I
Q
T
G
M
F
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGI8
1487
166060
A1357
L
E
I
T
S
N
Y
A
S
E
K
L
L
M
Q
Honey Bee
Apis mellifera
XP_396209
961
109321
I835
T
L
V
L
L
T
D
I
F
K
G
S
D
I
K
Nematode Worm
Caenorhab. elegans
O18017
988
110641
M862
D
L
L
R
I
D
S
M
T
Q
I
K
V
T
K
Sea Urchin
Strong. purpuratus
XP_001175892
1394
152920
K1261
A
Y
G
I
L
K
K
K
D
F
Q
R
G
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P35187
1447
163819
I1312
I
L
K
K
M
A
A
I
L
P
M
N
D
S
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
96.1
N.A.
N.A.
76.9
21.2
N.A.
46.3
47.9
50.8
41.6
N.A.
27.8
30.9
26.5
31.5
Protein Similarity:
100
99.2
97.7
N.A.
N.A.
85.2
30.9
N.A.
50.1
60.7
66.6
54
N.A.
47
47.1
40.2
47.6
P-Site Identity:
100
100
100
N.A.
N.A.
6.6
0
N.A.
0
60
80
6.6
N.A.
6.6
20
0
6.6
P-Site Similarity:
100
100
100
N.A.
N.A.
20
13.3
N.A.
26.6
80
80
13.3
N.A.
33.3
26.6
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
0
8
15
15
0
0
0
0
0
22
8
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
8
15
15
0
15
0
0
0
15
8
8
% D
% Glu:
0
8
0
8
8
0
0
0
36
8
0
0
0
8
36
% E
% Phe:
8
0
0
0
0
0
0
0
8
8
0
0
0
8
0
% F
% Gly:
0
0
22
8
8
0
0
0
0
0
8
8
8
0
8
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
43
8
8
8
8
0
8
15
8
8
8
8
0
8
0
% I
% Lys:
8
8
8
8
8
43
8
15
0
8
15
15
0
8
15
% K
% Leu:
15
29
8
36
15
0
0
0
15
8
0
15
22
0
0
% L
% Met:
0
0
0
8
8
0
0
8
0
0
8
0
8
8
0
% M
% Asn:
8
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
8
0
15
0
0
36
0
8
% P
% Gln:
0
0
0
0
29
0
8
0
0
15
15
0
0
0
15
% Q
% Arg:
0
0
0
8
0
0
0
8
0
0
0
8
0
0
0
% R
% Ser:
0
22
0
8
8
8
8
36
8
0
8
29
0
22
8
% S
% Thr:
8
0
8
8
0
8
0
0
8
0
43
8
0
8
0
% T
% Val:
0
0
43
0
0
8
0
0
8
0
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
36
0
8
0
0
0
% W
% Tyr:
0
15
0
0
0
0
43
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _